Fluticasone
is a steroid. It prevents the release of substances
in the body that cause inflammation. Salmeterol
is a bronchodilator. It works by relaxing muscles
in the airways to improve breathing. Advair Diskus
(Fluticasone and Salmeterol) inhalation is used
to prevent asthma attacks. It is also used to
prevent flare-ups or worsening of chronic obstructive
pulmonary disease (COPD) associated with chronic
bronchitis and/or emphysema.
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Manufacturer
Name : A
Product Category: Asthma
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Fluticasone
is a steroid. It prevents the release of substances
in the body that cause inflammation. Salmeterol
is a bronchodilator. It works by relaxing muscles
in the airways to improve breathing. Advair Diskus
(Fluticasone and Salmeterol) inhalation is used
to prevent asthma attacks. It is also used to
prevent flare-ups or worsening of chronic obstructive
pulmonary disease (COPD) associated with chronic
bronchitis and/or emphysema.
Synonyms: Cutivate, Flixonase, Flixotide, Flonase,
Flovent Diskus, Flunase, Seretide
What is Advair Diskus (fluticasone and salmeterol)?
Fluticasone is a steroid. It prevents the release
of substances in the body that cause inflammation.
Salmeterol is a bronchodilator. It works by relaxing
muscles in the airways to improve breathing. Advair
Diskus (fluticasone and salmeterol) inhalation
is used to prevent asthma attacks. It is also
used to prevent flare-ups or worsening of chronic
obstructive pulmonary disease (COPD) associated
with chronic bronchitis and/or emphysema. Advair
Diskus (fluticasone and salmeterol) may also be
used for other purposes not listed in this medication
guide.
What is the most important information I should
know about fluticasone and salmeterol? Do not
use fluticasone and salmeterol to treat an asthma
attack that has already begun. Before using fluticasone
and salmeterol, tell your doctor if you have a
food or drug allergy, heart disease, high blood
pressure, a seizure disorder, an infection, a
weak immune system, diabetes, glaucoma, tuberculosis,
osteoporosis, a thyroid disorder, or liver disease.
Call your doctor right away if you feel that this
medicine is not working as well as usual, or if
it makes your condition worse. Salmeterol has
been shown to increase the risk of asthma-related
death. It is critical that you use only the prescribed
dose of this medicine and follow all patient instructions
for safe use of the medication.
What should I discuss with my healthcare provider
before using this medication? Do not use this
medication if you are allergic to fluticasone
(Flonase, Flovent), salmeterol (Serevent), or
milk proteins, or if you are having an asthma
attack or severe COPD symptoms. Salmeterol has
been shown to increase the risk of asthma-related
death. It is critical that you use only the prescribed
dose of this medicine and follow all patient instructions
for safe use of the medication. If you have any
of these other conditions, you may need a dose
adjustment or special tests to safely use this
medication: ?a food or drug allergy; ?heart disease
or high blood pressure; ?epilepsy or other seizure
disorder; ?an infection of any kind; ?a weak immune
system; ?diabetes; ?glaucoma; ?tuberculosis; ?osteoporosis;
?a thyroid disorder; or ?liver disease. FDA pregnancy
category C. It is not known whether fluticasone
and salmeterol is harmful to an unborn baby. Before
using this medication, tell your doctor if you
are pregnant or plan to become pregnant during
treatment. It is not known whether fluticasone
and salmeterol passes into breast milk or if it
could harm a nursing baby. Do not use fluticasone
and salmeterol inhalation without telling your
doctor if you are breast-feeding a baby. Advair
Diskus (fluticasone and salmeterol) inhalation
can affect growth in children. Talk with your
doctor if you think your child is not growing
at a normal rate while using this medication.
Long-term use of steroids may lead to bone loss
(osteoporosis), especially if you smoke, if you
do not exercise, if you do not get enough vitamin
D or calcium in your diet, or if you have a family
history of osteoporosis.
How should I use this medication? Use this medication
exactly as it was prescribed for you. Do not use
the medication in larger amounts, or use it for
longer than recommended by your doctor. Follow
the directions on your prescription label. This
medication comes with patient instructions for
safe and effective use, and directions for priming
the inhaler device if needed. Follow these directions
carefully. Do not use fluticasone and salmeterol
inhalation to treat an asthma attack that has
already begun. It will not work fast enough. Use
only a fast-acting inhalation medication. Advair
Diskus is a powder form of fluticasone and salmeterol
that comes with a special inhaler device pre-loaded
with blister packs containing measured doses of
the medicine. The device opens and loads a blister
each time you use the inhaler. This device is
not to be used with a spacer. Advair HFA is an
aerosol form of fluticasone and salmeterol that
comes in a canister that is used with an actuator
inhaler device. Use only the inhaler device provided
with Advair HFA. This device is not to be used
with a spacer. Shake the Advair HFA inhaler for
at least 5 seconds before each spray. Keep track
of the number of sprays you have used and throw
away the Advair HFA canister after 120 sprays,
even if it feels like there is still medicine
in it. If you also use a steroid medication, do
not stop using the steroid suddenly or you may
have unpleasant withdrawal symptoms. Talk with
your doctor about using less and less of the steroid
before stopping completely. Call your doctor right
away if any of your asthma medications do not
seem to work as well in treating or preventing
asthma attacks. An increased need for medication
could be an early sign of a serious asthma attack.
If you use a peak flow meter, call your doctor
if your numbers are lower than normal. Asthma
is usually treated with a combination of different
drugs. To best treat your condition, use all of
your medications as directed by your doctor. Do
not change your doses or medication schedule without
advice from your doctor. Carry an identification
card or wear a medical alert ID to let others
know that you may need an oral steroid in an emergency.
Store this medication at room temperature away
from moisture and heat. Keep the Advair HFA canister
away from high heat, such as open flame or in
a car on a hot day. The canister may explode if
it gets too hot.
What happens if I miss a dose? Use the medication
as soon as you remember. If it is almost time
for the next dose, skip the missed dose and wait
until your next regularly scheduled dose. Do not
use extra medicine to make up the missed dose.
What happens if I overdose? Seek emergency medical
attention if you think you have used too much
of this medicine. Overdose symptoms may include
angina or chest pain, fast or irregular heartbeats,
seizures, tremor, weakness, headache, nausea,
and vomiting.
What should I avoid while using this medication?
Do not use a second form of salmeterol (such as
Serevent) or use a similar inhaled bronchodilator
such as formoterol (Foradil) unless your doctor
has told you to. Advair Diskus (fluticasone and
salmeterol) can lower the blood cells that help
your body fight infections. Avoid being near people
who are sick or have infections. Call your doctor
for preventive treatment if you are exposed to
chicken pox or measles. These conditions can be
serious or even fatal in people who are using
steroid medicines.
This medication side effects Get emergency medical
help if you have any of these signs of an allergic
reaction: hives; difficulty breathing; swelling
of your face, lips, tongue, or throat. Call your
doctor at once if you have any of these serious
side effects: ?bronchospasm (wheezing, chest tightness,
trouble breathing); ?fast or uneven heart beats,
restless feeling, tremor; ?fever, chills, stabbing
chest pain, cough with yellow or green mucus;
?blurred vision, eye pain, or seeing halos around
lights; ?white patches or sores inside your mouth
or on your lips; or ?worsening asthma symptoms.
Less serious side effects include: ?headache,
dizziness; ?nausea, vomiting, diarrhea; ?dry mouth,
nose, or throat; ?stuffy nose, sinus pain, cough,
sore throat; or ?hoarseness or deepened voice.
This is not a complete list of side effects and
others may occur. Call your doctor for medical
advice about side effects.
What other drugs will affect this medication?
Before using fluticasone and salmeterol inhalation,
tell your doctor if you are using any of the following
drugs: ?amiodarone (Cordarone); ?a diuretic or
¶water pill÷; ?HIV medicines such as atazanavir
(Reyataz), ritonavir (Norvir), indinavir (Crixivan),
nelfinavir (Viracept), or saquinavir (Invirase);
?an MAO inhibitor such as isocarboxazid (Marplan),
tranylcypromine (Parnate), phenelzine (Nardil),
rasagiline (Azilect), or selegiline (Eldepryl,
Emsam); ?an antidepressant such as amitriptyline
(Elavil), desipramine (Norpramin), fluoxetine
(Prozac), nefazodone, or imipramine (Tofranil);
?antibiotics such as clarithromycin (Biaxin) or
telithromycin (Ketek); ?antifungal medications
such as ketoconazole (Nizoral) or itraconazole
(Sporanox); or ?a beta-blocker such as atenolol
(Tenormin), carvedilol (Coreg), metoprolol (Lopressor,
Toprol), and others. This list is not complete
and there may be other drugs that can interact
with fluticasone and salmeterol inhalation. Tell
your doctor about all the prescription and over-the-counter
medications you use. This includes vitamins, minerals,
herbal products, and drugs prescribed by other
doctors. Do not start using a new medication without
telling your doctor.
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